Smallpox

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Public Inquiries Hotline (Centers for Disease Control and Prevention): English (888) 246-2675 | Español (888) 246-2857 | TTY (866) 874-2646 Hours: Mon-Fri 8am-11pm EST; Sat-Sun 10am-8pm EST

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Smallpox Basics

• About the Smallpox Vaccination Program
• Smallpox Vaccination Program: Questions and Answers
• About the Disease  [En Español]
• About the Vaccine  [En Español]
• Vaccine Side Effects  [En Español]
• Who Should NOT Be Vaccinated  [En Español]
• Smallpox Vaccine and Heart Problems
• Information on Live Viruses and Vaccinia
   [En Español]
• Caring for the Smallpox Vaccination Site
   [En Español]
• Someone You Are Close to Is Getting the Vaccine: What You Should Know and Do
   [En Español]
• Questions and Answers about Smallpox
• Find Your Local Public Health Departmentx (National Association of County and City Health Officials)
• CDC Smallpox Website (Centers for Disease Control and Prevention)
• Smallpox (healthfinder)
• Smallpox  (MEDLINEplus)
• Smallpox Fact Sheets (World Health Organization)

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Principios de la Viruela

• Sobre la Enfermedad
• Sobre la Vacuna y la Vacunación
• Reacciones Posteriores a la Vacunación Contra la Viruela
• Vacunas de Virus Vivos y Vaccinia
• ¿Quiénes NO Deben Recibir la Vacuna Contra la Viruela?
• Cuidado del Sitio Donde se Aplicó la Vacuna
• Lo Que Debe Saber y Hacer Cuando Alguien Cercano a Usted se Vacune Contra la Viruela

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Information for Laboratory Professionals

• Smallpox: Laboratory Testing (Smallpox: Laboratory Testing - Centers for Disease Control and Prevention)
• Smallpox: Training and Education (Centers for Disease Control and Prevention)
• Fact Sheet: Specimen Collection of Smallpox (Vaccinia) Vaccine Virus (Fact Sheet: Specimen Collection of Smallpox (Vaccinia) Vaccine Virus - Centers for Disease Control and Prevention)
• Facts About the Laboratory Response Network (Centers for Disease Control and Prevention)
• Smallpox Response Plan and Guidelines (Version 3.0) (Centers for Disease Control and Prevention)

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Information for Kids, Teens, Parents

• Smallpox Information for Kids (Nemours Foundation)
• Smallpox Information for Teens (Nemours Foundation)
• Smallpox Information for Parents (American Academy of Pediatrics)

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Information for the Media

• Press Release: HHS Issues Final Rule for Smallpox Vaccine Injury Compensation Program, June 16, 2006 (U.S. Department of Health and Human Services)
• Press Release: United States Pledges 20 Million Doses of Smallpox Vaccine to Global Stockpile, December 10, 2004 (U.S. Department of Health and Human Services)
• Press Release: HHS Awards $232 Million in Biodefense Contracts for Vaccine Development, October 7, 2004 (U.S. Department of Health and Human Services)
• Press Release: Secretary Thompson to Release $100 MILLION to Assist States with Smallpox Vaccination Programs, May 5, 2003 (U.S. Department of Health and Human Services)
• Transcript: Update on Smallpox Vaccination Program, March 25, 2003 (Centers for Disease Control and Prevention)
• Press Release:
  Temporary Deferral Recommended for Heart Patients Volunteering for Smallpox Vaccination, March 25, 2003 (Centers for Disease Control and Prevention)
• Press Release: HHS Secretary Authorizes Smallpox Vaccination Program, February 24, 2003 (U.S. Dept. of Health and Human Services)
• Press Release: HHS Announces Contracts to Develop Safer Smallpox Vaccines, February 25, 2003 (U.S. Dept. of Health and Human Services)
• Press Release: HHS Proposes Smallpox Vaccination Compensation Plan, March 5, 2003 (U.S. Dept. of Health and Human Services)
• Transcript:
  Update on Smallpox Vaccination Program, March 25, 2003 (Centers for Disease Control and Prevention)
• Smallpox Vaccination Program: Vaccine Doses Shipped and Released for Use  (Centers for Disease Control and Prevention)
• Press Release:
  FDA Announces Smallpox Vaccine Guidance for Blood Industry, December 30, 2002 (Food and Drug Administration)
• Transcript:
  HHS Teleconference on Smallpox Policy, December 14, 2002 (Centers for Disease Control and Prevention)
• Transcript:
  President Announces Smallpox Vaccination Program, December 13, 2002 (The White House)
• Press Release: Comprehensive Information Provided on www.smallpox.gov, December 13, 2002 (U.S. Dept of Health & Human Services)
• Press Release:
  CDC initial review of state smallpox vaccination plans complete, December 12, 2002 (Centers for Disease Control and Prevention)
• Transcript:
  ACIP Smallpox Vaccine Meeting Press Briefing, October 17, 2002 (Centers for Disease Control and Prevention)
• Press Release: HHS May Acquire More Than 75 Million Doses of Smallpox Vaccine, March 29, 2002 (U.S. Dept of Health & Human Services)
• Press Release: NIAID Study Results Support Diluting Smallpox Vaccine Stockpile to Stretch Supply, March 28, 2002 (U.S. Dept of Health & Human Services)
• Press Release: HHS Awards $428 Million Contract to Produce Smallpox Vaccine, November 28, 2001 (U.S. Dept of Health & Human Services)
• Transcript:
  CDC Teleconference Update on Smallpox Educational Activities and West Nile Virus, December 19, 2002 (Centers for Disease Control and Prevention)
• Press Release:
  HHS and CDC Continuing to Educate Health Care Personnel and General Public About Smallpox, December 19, 2002 (Centers for Disease Control and Prevention)

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Information for the Military

• Smallpox Vaccination Program (U.S. Department of Defense)

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Information for Primary Health Care Providers

General:

• Smallpox: Diagnosis/Evaluation (Centers for Disease Control and Prevention)
• Vaccine/Vaccination Information
• Worksheet for evaluating the patient with possible smallpox (PDF - 186KB KB) (Centers for Disease Control and Prevention)
• Smallpox Vaccination Program Implementation: Information to Support Public Health and Clinical Personnel Planning for Smallpox Vaccination (Centers for Disease Control and Prevention)
• Guidance for Post-Event Smallpox Planning (Centers for Disease Control and Prevention)

Text Book Chapters:

• Chapter 21: Epidemiology and Prevention of Vaccine-Preventable Diseases, in Pink Book (PDF - 901KB) (Centers for Disease Control and Prevention)
• Chapter 6: Smallpox and Vaccinia by D.A. Henderson and B. Moss in Vaccines, 3rd Ed. by S.A .Plotkin and W.A. Orenstein, Saunders Co.,1999  (National Center for Biotechnology Information)

Webcasts:

• Smallpox: Addressing the Smallpox Threat: Issues, Strategies and Tools, March 3, 2003 (Agency for Healthcare Research and Quality)
• CDC Bioterrorism Update: Smallpox Preparedness, December 5, 2002 (Centers for Disease Control and Prevention)
• 2002 International Conference on Emerging Infectious Diseases:Smallpox Response (multiple sessions), March 25, 2002 (Centers for Disease Control and Prevention)
• CDC Bioterrorism Update: Smallpox Preparedness - Considerations for Response Team Volunteers, December 5, 2002 (Centers for Disease Control and Prevention)
• Smallpox: Considerations for Response Team Volunteers (Centers for Disease Control and Prevention, 12/20/2002)
• Smallpox: Smallpox and Vaccinia Laboratory Testing: A National Training Initiative (Centers for Disease Control and Prevention, 1/29/2003)
• Clinical Management of Adverse Events Following Smallpox Vaccination: A National Training Initiative (Centers for Disease Control and Prevention, 2/4/2003)

Images:

• Smallpox Disease Images (Centers for Disease Control and Prevention)
• Vaccine Reaction Images (Centers for Disease Control and Prevention)
• Poster: Evaluating Patients for Smallpox [PDF - 1.2MB] (PDF - 1.2MB KB) (Centers for Disease Control and Prevention)
• Slide Set on the Diagnosis of Smallpox (Centers for Disease Control and Prevention)
• Clinical Images (World Health Organization)

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Information for Public Health Professionals

• Smallpox Resources for Health Officials  (Centers for Disease Control and Prevention)
• Smallpox: Addressing the Smallpox Threat: Issues, Strategies and Tools, March 3, 2003 (Agency for Healthcare Research and Quality)
• Smallpox Response Plan and Guidelines (Version 3.0) (Centers for Disease Control and Prevention)
• Guidelines for Large Scale Smallpox Vaccination Clinics, Smallpox Response Plan and Guidelines (Version 3.0) (PDF - 952 KB)  (WPD - 748 KB) (Centers for Disease Control and Prevention)
• Smallpox: Infection Control (Centers for Disease Control and Prevention)
• Infection Control Measures for Healthcare and Community Settings and Quarantine Guidelines, Smallpox Response Plan and Guidelines (Version 3.0) (Centers for Disease Control and Prevention)
• Smallpox Surveillance and Case Reporting; Contact Identification, Tracing, Vaccination, and Surveillance; and Epidemiologic Investigation (Centers for Disease Control and Prevention)
• Environmental Control of Smallpox Virus (Centers for Disease Control and Prevention )
• Worksheet for evaluating the patient with possible smallpox (PDF - 186KB KB) (Centers for Disease Control and Prevention)
• Guidance for Post-Event Smallpox Planning (Centers for Disease Control and Prevention)
• Smallpox Vaccination Program Implementation: Information to Support Public Health and Clinical Personnel Planning for Smallpox Vaccination (Centers for Disease Control and Prevention)
• Smallpox Pre-Vaccination Information Packet (Centers for Disease Control and Prevention)

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Clinical Trials

• Smallpox Clinical Trials Information (National Institutes of Health)

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CDC's Smallpox Response Plan and Guidelines

• Smallpox Response Plan and Guidelines (Version 3.0) (Centers for Disease Control and Prevention)
• Guidelines for Large Scale Smallpox Vaccination Clinics, Smallpox Response Plan and Guidelines (Version 3.0) (PDF - 952 KB)  (WPD - 748 KB) (Centers for Disease Control and Prevention)

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Reference Materials

• Smallpox: References (Centers for Disease Control and Prevention)
• Biodefense: NIAID Research (National Institute of Allergy and Infectious Diseases)

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Vaccine/Vaccination Information

For Citizens

• Vaccine Overview [En Español]
• Reactions after Smallpox Vaccination
   [En Español]
• People Who Should NOT Get the Smallpox Vaccine
   [En Español]
• Caring for the Smallpox Vaccination Site
   [En Español]
• Someone You Are Close to Is Getting the Vaccine: What You Should Know and Do
   [En Español]
• Information on Live Viruses and Vaccinia
   [En Español]
• FAQs about Smallpox: The Disease and the Vaccine
• Information for People Selected for Smallpox Response Teams (Centers for Disease Control and Prevention)
   [En Español]
• Smallpox Pre-Vaccination Information Packet (Centers for Disease Control and Prevention)

For Blood Donation Organizations

• Guidance for Industry: Recommendations for Deferral of Donors and Quarantine and Retrieval of Blood and Blood Products in Recent Recipients of Smallpox Vaccine (Vaccinia Virus) and Certain Contacts of Smallpox Vaccine Recipients (Food and Drug Administration)

For Clinicians

• Smallpox Vaccination Overview for Clinicians (Centers for Disease Control and Prevention)
• Smallpox Vaccine Contraindications (Centers for Disease Control and Prevention)
• Smallpox Vaccination and Adverse Events Training Module: Contraindications (Centers for Disease Control and Prevention)
• Adverse Reactions Following Smallpox Vaccination (Centers for Disease Control and Prevention)
• Medical Management of Smallpox (Vaccinia) Vaccine Adverse Reactions: Vaccinia Immune Globulin and Cidofovir (Centers for Disease Control and Prevention)
• Smallpox Vaccine: Adverse Event Rates, 1968 (Centers for Disease Control and Prevention)
• Smallpox Vaccination and Adverse Events Training Module: Vaccination Method (Centers for Disease Control and Prevention)
• Smallpox Vaccination and Adverse Events Training Module: Preventing Contact Transmission (Centers for Disease Control and Prevention)
• Smallpox Vaccination and Adverse Events Training Module: Vaccinia Immune Globulin-VIG (Centers for Disease Control and Prevention)
• Recommendations for Using Smallpox Vaccine in a Pre-Event Smallpox Vaccination Program (Centers for Disease Control and Prevention)
• Guidelines for Large Scale Smallpox Vaccination Clinics, Smallpox Response Plan and Guidelines (Version 3.0) (PDF - 952 KB)  (WPD - 748 KB) (Centers for Disease Control and Prevention)
• Smallpox Vaccination: Information for Health Professionals (Centers for Disease Control and Prevention)
• Clinical Evaluation Tools for Smallpox Vaccine Adverse Reactions (Centers for Disease Control and Prevention)
• Smallpox (Vaccinia) Vaccine Adverse Event Reporting (Centers for Disease Control and Prevention)

Official Vaccination Clinic Guide

• Guidelines for Large Scale Smallpox Vaccination Clinics, Smallpox Response Plan and Guidelines (Version 3.0) (PDF - 952 KB)  (WPD - 748 KB) (Centers for Disease Control and Prevention)
• Vaccination Clinic Guide: Fact Sheet 9/23/2002 (Centers for Disease Control and Prevention)
• Vaccination Clinic Guide: Press Release/ Response Plan and Clinic Guidelines 9/23/2002 (Centers for Disease Control and Prevention)
• Vaccination Clinic Guide: Transcript of Press Conference 9/23/2002 (Centers for Disease Control and Prevention)

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Smallpox Vaccine Injury Compensation Program

• Smallpox Vaccine Injury Compensation Program Home (Health Resources and Services Administration)
• Administrative Implementation (Health Resources and Services Administration )
• Covered Injuries (Health Resources and Services Administration)

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