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Last Updated: 15 Sep 08
    Rabies
    Rhabdoviridae
 


picture of rabies
Rabies is a preventable viral disease of mammals most often transmitted through the bite of a rabid animal. The vast majority of rabies cases reported to the Centers for Disease Control and Prevention (CDC) each year occur in wild animals like raccoons, skunks, bats, and foxes. Domestic animals account for less than 10% of the reported rabies cases, with cats, cattle, and dogs most often reported rabid. Rabies virus infects the central nervous system, causing encephalopathy and ultimately death. Early symptoms of rabies in humans are nonspecific, consisting of fever, headache, and general malaise. As the disease progresses, neurological symptoms appear and may include insomnia, anxiety, confusion, slight or partial paralysis, excitation, hallucinations, agitation, hypersalivation, difficulty swallowing, and hydrophobia (fear of water). Death usually occurs within days of the onset of symptoms.
 
    VIS   SHORTAGES       PACKAGE INSERTS          INFO PAPER

NEWSmore...
dot MSNBC 26 Jun 08
Rabies vaccines in short supply

CLINICALmore...
  Important Dosing and Administration Information - HyperRAB™ S/D  21 Feb 08
 Revised Directions for Use of 2 mL Prefilled Syringe
  Compendium of Animal Rabies Prevention and Control, 2007  27 Dec 06

ACIP GUIDELINESmore...
  Human Rabies Prevention - United States, 2008  23 May 08
 Recommendations of the Advisory Committee on Immunization Practices (ACIP)
  Compendium of Animal Rabies Prevention and Control, 2008  18 Apr 08
 National Association of State Public Health Veterinarians, Inc.

SHORTAGEmore...
  MMQC-08-1396  11 Sep 08
 NOVARTIS AND SANOFI-AVENTIS / RABAVERT AND IMOVAX RABIES VACCINE SEVERE SHORTAGE / INFORMATION BULLETIN

MMQC MESSAGESmore...
  MMQC-08-1396  11 Sep 08
 NOVARTIS AND SANOFI-AVENTIS / RABAVERT AND IMOVAX RABIES VACCINE SEVERE SHORTAGE / INFORMATION BULLETIN
  MMQC-08-1172  06 May 08
 NOVARTIS AND SANOFI PASTEUR / RABAVERT AND IMOVAX RABIES VACCINE / INFORMATION BULLETIN
  MMQC-08-1101  28 Feb 08
 TALECRIS BIOTHERAPEUTICS / HYPERRAB [RABIES IMMUNE GLOBULIN (HUMAN)] / IMPORTANT SAFETY INFORMATION - REVISED DIRECTIONS / CDC HEALTH ADVISORY NETWORK

LIBRARYmore...
Disease: Rabies
Author(s): CDC
Title: Manufacturer’s Recall of Human Rabies Vaccine — April 2, 2004
Publication: MMWR Dispatch Vol. 53 / April 2, 2004
Date: 2004
Subject: Vaccine-Safety
Link: http://www.cdc.gov/mmwr/pdf/wk/mm53d402.pdf
File:
 
 


PACKAGE INSERTmore...
  HyperRAB™ S/D, Rabies Immune Globulin (Human) (Talecris)
 Package Insert
  Imovax (Sanofi-Pasteur)
 Package Insert
  Imogam (Sanofi-Pasteur)
 Rabies Immune Globulin (Human) USP
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