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GENETIC INDUCTION OF ANTI-VIRAL IMMUNE RESPONSE AND GENETIC VACCINE FOR FILOVIRUS
An approach to genetic vaccine methodology is described. A genetic construction encoding antigenic determinants of a filovirus is transfected into cells of the vaccinated individuals using a particle acceleration protocol so as to express the viral antigens in healthy cells to produce an immune response to those antigens.
Number:6,200,959
Date:2001-03-13
Type: Issued
Category: Vaccine
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Lab:RIID
Inventor(s):HAYNES, J.; SCHMALJOHN, C.; FULLER, D.; SCHMALJOHN, A.; JAHRLING, P.