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Lipid Metabolism and the Pathophysiology of Obesity
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In
the midst of an epidemic of obesity, with many likely and
poorly understood causes, NIH has developed a multi-pronged
attack on the problem. This workshop
supported by NIDDK, NHLBI, NIA,
NICHD, NIGMS and ODS will
focus attention on how alterations in lipid metabolism and signaling
impact the
development of obesity and its complications.
Lipids, whether derived from the diet or from cellular metabolic
activities, play a major role in overall energy balance, and any
number of alterations in
lipid metabolism may contribute to the disease state. Since lipids
are used as sources of fuel for energy production, as structural
elements, and as signaling
molecules, there are many different levels at which further understanding
is needed. For example, little is known about events in specific
cells and tissues
that lead to greater fat accumulation, alterations in fat deposition,
generation of harmful metabolites, and development of specific cellular
injuries. This workshop
will attempt to define the current state-of-the-art and provide a
blueprint for development of new initiatives designed to address
the role of lipid metabolism
in the obesity epidemic. The invited speakers and attendees will
be asked to help provide this blueprint through
a variety of inputs, including platform presentations, posters,
and discussions.
COMMENTS
The organizers welcome any comments regarding the role of the
NIH in addressing the obesity epidemic, areas where progress
is needed, resources or technologies
that are lacking, and ways in which NIDDK, NHLBI, NIA, NICHD, and NIGMS
can be most effective.
Submit comments |
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U.S. Department of Health and Human Services
National Institutes of Health
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