You are here

Share:

Product Type

Development Stage

Therapeutic Area

Search Technologies

Showing 1-11 of 11 results found

Engineered Biological Pacemakers

The National Institute on Aging's Cellular Biophysics Section is seeking statements of capability or interest from parties interested in collaborative research to further develop, evaluate, or commercialize biological pacemakers.
  • Devices

Method and device for selectively labeling RNA

The National Cancer Institute's Structure Biophysics Lab seeks partners interested in licensing or co-developing a technology to site-specifically label RNA.
  • Research Materials
  • Devices
  • Diagnostics

Automated Cancer Detection (CAD) Using MRI

The inventions listed are owned by an agency of the U.S. Government and are available for licensing in the U.S. in accordance with 35 U.S.C. 209 and 37 CFR Part 404 to achieve expeditious commercialization of results of federally-funded research and development. Foreign patent applications are filed on selected inventions to extend market coverage for companies and may also be available for licensing.
  • Devices
  • Diagnostics

Method for Targeted Therapeutic Delivery of Proteins into Cells

The Protein Expression Laboratory at the National Cancer Institute in Frederick, MD is seeking statements of capability or interest from parties interested in collaborative research to further develop a platform technology for the targeted intra-cellular delivery of proteins using virus-like particles (VLPs).
  • Devices
  • Therapeutics
  • Vaccines

Therapeutic for Glioblastoma Multiforme and Other Cancers using Induced Electric Fields

Glioblastoma Multiforme (GBM) is the most common and devastating form of brain cancer. Despite existing conventional therapies, including an initial surgical resection followed by chemotherapy and radiation, GBM has a median survival of approximately 15 months and a two-year survival rate of 30%. The NICHD seeks parties interested in collaborative research to co-develop or license a cancer therapy device that uses induced electric fields.
  • Devices
  • Therapeutics

Detection of novel endocrine-disrupting chemicals in water supplies

Testing for biological activity of glucocorticoids and many other steroid endocrine-disrupting chemicals (EDCs) has not been previously performed. An automated, highly reproducible, and low cost assay detects biologically active steroidal EDCs and is suitable for wide application in testing water samples. The National Cancer Institute seeks partners for collaborative co-development research and/or licensing to move this technology into the public domain.
  • Devices
  • Diagnostics
  • Research Materials

In Vivo Imaging of Tissue Physiological Function using EPR Spectroscopy

Electron paramagnetic resonance (EPR) is a technique for studying chemical species that have one or more unpaired electrons.  The current invention describes Echo-based Single Point Imaging (ESPI), a novel EPR image formation strategy that allows in vivo imaging of physiological function.  The National Cancer Institute's Radiation Biology Branch is seeking statements of capability or interest from parties interested in in-licensing an in vivo imaging using Electron paramagnetic resonance (EPR) to measure active oxygen species.
  • Devices

Novel Fixative for Improved Biomolecule Quality from Paraffin-Embedded Tissue

Researchers in the National Cancer Institute’s Laboratory of Pathology have developed an improved tissue fixative solution that is formaldehyde-free. This novel fixative, BE70, significantly improves DNA, RNA, and protein biomolecule integrity in histological samples compared to traditional fixatives. Additionally, BE70 is compatible with current protocols and does not alter tissue processing. NCI seeks partners to license this technology.
  • Devices
  • Diagnostics
  • Research Materials

Holders for growing mammalian cells on grids for electron microscopy

The technology is a tool used to hold transmission electron microscopy grids to grow adherent mammalian cells on and the 3D printing software to create the holder. The TEM cell grid holder solves the difficulty of lifting the TEM grid out of a plate without bending or damaging the grid. Researchers at the NCI seek licensing for the transmission electron microscopy grid holder.
  • Devices
  • Research Materials
  • Software

Device to guide oxygen over cells for photo-oxidation

Device is used to guide a stream of oxygen or carbon dioxide over a dish of cells during fluorescence microscopy. Invention includes the 3D printing software to create the device. The device makes it possible to easily provide a steady source of oxygen or carbon dioxide to cells while operating a fluorescent microscope to oxidize fluorophores for later visualization in electron microscopy. NCI seeks commercial partners to license this technology.
  • Devices
  • Research Materials
  • Software