Publications |
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HERE to search NCBI PubMed for publications by Alexander
Wlodawer. |
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| SELECTED
RECENT PUBLICATIONS: |
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| B. Rupp, A.
Wlodawer, W. Minor, J. R. Helliwell and M. Jaskolski. 2016. Correcting the
record of structural publications requires joint effort of the community and
journal editors. FEBS Journal, in press. |
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| A. R. Leal,
R. Cruz, D. Bur, P. F. Huesgen, R. Faro, B. Manadas, A. Wlodawer, C. Faro and
I. Simões. 2016. Enzymatic properties, evidence for in vivo expression,
and intracellular localization of shewasin D, the pepsin homolog from
Shewanella denitrificans. Scientific Reports, 6:23869. |
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| M. Li, O.
Kandror, T. Akopian, P. Dharkar, A. Wlodawer, M. R. Maurizi and A. L. Goldberg.
2016. Structure and functional properties of the active form of the proteolytic
complex, ClpP1P2, from Mycobacterium tuberculosis. J. Biol. Chem., 291,
7465-7476. |
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| M.
Jakób, J. Lubkowski, B. O'Keefe and A. Wlodawer. 2015. Structure of a
lectin from sea mussel Crenomytilus grayanus (CGL). Acta Crystallogr.,
F71, 1429-1436. |
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| Z. Dauter
and A. Wlodawer. 2015. On the accuracy of unit-cell parameters in protein
crystallography. Acta Crystallogr., D71, 2217-2226. |
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| M. Li, A.
Gustchina, R. Cruz, M. Simões, P. Curto, J. Martinez, C. Faro, I.
Simões and A. Wlodawer. 2015. Structure of RC1339/APRc from Rickettsia
conorii, a retropepsin-like aspartic protease. Acta Crystallogr., D71,
2109-2118. |
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| D. Zhou, D.
Hansen, I. G. Shabalin, A. Gustchina, D. F. Vieira, M. V. de Brito, A. P. U.
Araújo, M. L. V. Oliva and A. Wlodawer. 2015. Structure of rBbKI, a
disulfide-free plasma kallikrein inhibitor. Acta Crystallogr., F71,
1055-1062. |
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| I. G.
Shabalin, Z. Dauter, M. Jaskolski, W. Minor and A. Wlodawer. 2015.
Crystallography and chemistry should always go together: a cautionary tale of
protein complexes with cisplatin and carboplatin. Acta Crystallogr.,
D71, 1965-1979. |
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| A.
Pomés, M. Chruszcz, A. Gustchina and A. Wlodawer. 2015. Interfaces
between allergen structure and diagnosis: know your epitopes. Curr. Allergy
Asthma Rep., 15:8. |
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| T. Moulaei,
K. B. Alexandre, S. R. Shenoy, J. Meyerson, L. R. H. Krumpe, B. Constantine, J.
Wilson, R. Buckheit, J. B. McMahon, S. Subramaniam, A. Wlodawer and B. R.
O'Keefe. 2015. Griffithsin tandemers: flexible and potent lectin inhibitors of
the human immunodeficiency virus. Retrovirology, 12:6. |
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| H. Xiao, B.
C. Bryksa, P. Bhaumik, A. Gustchina, Y. Kiso, S. Q. Yao, A. Wlodawer and R. Y.
Yada. 2014. The zymogen of plasmepsin V from Plasmodium falciparum is
enzymatically active. Molec. Biochem. Parasitology, 197,
56-63. |
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| A.S. Aranko,
A. Wlodawer and H. Iwaï. 2014. Nature's recipe for splitting inteins.
Protein Eng. Des. Sel., 27, 263-271. |
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| R. Cruz, P.
Huesgen, S. P. Riley, A. Wlodawer, C. Faro, C. M. Overall, J. J. Martinez and
I. Simões. 2014. RC1339/APRc from Rickettsia conorii is a novel aspartic
protease with properties of retropepsin-like enzymes. PLoS Pathog., 10,
e1004324. |
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| D. Zhou, W.
Visessanguan, S. Chaikaew, S. Benjakul, K. Oda and A. Wlodawer. 2014.
Crystallization and preliminary crystallographic analysis of histamine
dehydrogenase from Natrinema gari BCC 24369. Acta Crystallogr., F70,
942-945. |
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| Z. Dauter,
A. Wlodawer, W. Minor, M. Jaskolski and B. Rupp. 2014. Avoidable errors in
deposited macromolecular structures - an impediment to efficient data mining.
IUCrJ, 1, 179-193. |
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| A. S.
Aranko, J. S. Oeemig, D. Zhou, T. Kajander, A. Wlodawer and H. Iwaï. 2014.
Structure-based engineering and comparison of novel split inteins for protein
ligation by protein trans-splicing. Mol. Biosyst., 10,
1023-1034. |
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| H. Zheng, J.
Hou, M. D. Zimmerman, A. Wlodawer and W. Minor. 2014. The future of
crystallography in drug discovery. Expert Opin. Drug Discov., 9,
125-137. |
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| M. J. Domagalski, H.
Zheng, M. D. Zimmerman, Z. Dauter, A. Wlodawer and W. Minor. 2014. The quality
and validation of structures from Structural Genomics.Structural Genomics:
General Applications, Methods in Molecular Biology, vol. 1091, Y. W. Chen
ed., pp. 297-314, Humana Press. |
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E. Gustchina, M. Li,
R. Ghirlando, P. Schuck, J. M. Louis, J. Pierson, P. Rao, S. Subramaniam, A.
Gustchina, G. M. Clore and A. Wlodawer. 2013. Complexes of neutralizing
and non-neutralizing affinity matured Fabs with a mimetic of the internal
trimeric coiled-coil of HIV-1 gp41. PLoS ONE, 8,
e78187.
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J. Yao, A. Wlodawer
and H. Guo. 2013. Understanding the autocatalytic process of pro-kumamolisin
activation from Molecular Dynamics and QM/MM free energy simulations. Chem.
Eur. J., 19, 10849-10852.
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R. S. Ferreira, D.
Zhou, J. G. Ferreira, M. C. C. Silva, R. A. Silva-Lucca, R. Mentele, E. J.
Paredes-Gamero, T. C. Bertolin, M. T. S. Correia, P. M. G. Paiva, A. Gustchina,
A. Wlodawer and M. L. V. Oliva. 2013. Crystal structure of Crataeva tapia
bark protein (CrataBL) and its effect in human prostate cancer cell lines.
PLoS ONE, 8, e64426.
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| D. Zhou, Y. A. Lobo, I. F.
C. Batista, R. Marques-Porto, A. Gustchina, M. L. V. Oliva and A. Wlodawer.
2013. Crystal structures of a plant trypsin inhibitor from Enterolobium
contortisiliquum (EcTI) and of its complex with bovine trypsin. PLoS
ONE, 8, e62252. |
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F. Zhang, B.
Walcott, D. Zhou, A. Gustchina, Y. Lasanajak, D. F. Smith, R. S. Ferreira, M.
T. S. Correia, P. M. G. Paiva, N. V. Bovin, A. Wlodawer, M. L. V. Oliva
and R. J. Linhardt. 2013. Structural studies on the interaction of Crataeva
tapia bark protein with heparin and other glycosaminoglycans.
Biochemistry, 52, 2148-2156.
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| N. V. Pletneva, V. Z.
Pletnev, E. Souslova, D. M. Chudakov, S. Lukyanov, V. I. Martynov, S.
Arkhipova, I. Artemyev, A. Wlodawer, Z. Dauter and S. Pletnev. 2013. Yellow
fluorescent protein phiYFPv (phialidium). Crystal structure and
structure-based mutagenesis. Acta Crystallogr. D69, 1005-1012.
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| K. Matúz, J.
Mótyán, M. Li, A. Wlodawer and J. TÅ‘zsér.
2012. Inhibition of XMRV and HIV-1 proteases by pepstatin A and
acetyl-pepstatin. FEBS J., 279, 3276-3286. |
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| M. Acchione, Y-C. Lee, M.
E. DeSantis, C. Lipschultz, A. Wlodawer, M. Li, A. Shanmuganathan, R. L.
Walter, S. Smith-Gill and J. J. Barchi Jr. 2012. Specific Fluorine Labeling of
HyHEL10 Antibody Affects Antigen Binding and Dynamics. Biochemistry,
51, 6017-6027. |
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| S. Pletnev, N. V.
Pletneva, E. A. Souslova, D. M. Chudakov, S. Lukyanov, A. Wlodawer, Z. Dauter
and V. Pletnev. 2012. Structural basis for bathochromic shift of fluorescence
in far-red fluorescent proteins eqFP650 and eqFP670. Acta Crystallogr.
D68, 1088-1097. |
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| J. S. Oeemig, D. Zhou, T.
Kajander, A. Wlodawer and H. Iwaï. 2012. NMR and crystal structures of the
Pyrococcus horikoshii RadA intein guide a strategy for engineering a
highly efficient and promiscuous intein. J. Mol. Biol. 421, 85-99.
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| D. Zhou, S. Chung, M.
Miller, S. F. J. Le Grice and A. Wlodawer. 2012. Crystal
structures of the reverse transcriptase-associated ribonuclease H domain of
xenotropic murine leukemia-virus related virus. J. Struct. Biol., 177,
638-645. |
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| S. Pletnev, F. V. Subach,
Z. Dauter, A. Wlodawer and V. V. Verkhusha. 2012. A structural basis for
reversible photoswitching of absorbance spectra in red fluorescent protein
rsTagRFP. J. Mol. Biol., 417, 144-151. |
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E. Peletskaya, M.
Andrake, A. Gustchina, G. Merkel, J. Alexandratos, D. Zhou, R. S. Bojja, T.
Satoh, M. Potapov, A. Kogon, V. Potapov, A. Wlodawer and A. M. Skalka. 2011.
Localization of ASV integrase DNA contacts by site-directed crosslinking and
their structural analysis. PLoS ONE, 6:e27751.
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M. Li, A. Gustchina,
K. Matúz, J. Tözsér, S. Namwong, N. E. Goldfarb, B. M. Dunn
and A. Wlodawer. 2011. Structural and biochemical characterization of the
inhibitor complexes of xenotropic murine leukemia virus-related virus protease.
FEBS J., 278, 4413-4424.
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| P. Bhaumik, H. Xiao, K.
Hidaka, A. Gustchina, Y. Kiso, R. Y. Yada and A. Wlodawer. 2011. Structural
insights into activation and inhibition of histo-aspartic protease from
Plasmodium falciparum, Biochemistry, 50, 8862-8879. |
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J. Glesner, S.
Wünschmann, M. Li, A. Gustchina, A. Wlodawer, M. Himly, M. D. Chapman and
A. Pomés. 2011. Mechanisms of allergen-antibody interaction of cockroach
allergen Bla g 2 with monoclonal antibodies that inhibit IgE antibody binding.
PLoS ONE, 6, e22223.
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B. C. Bryksa, P.
Bhaumik, E. Magracheva, D. C. De Moura, M. Kurylowicz, A. Zdanov, J. R.
Dutcher, A. Wlodawer and R. Y. Yada. 2011. Crystal structure and proposed
protein-membrane interactions of a saposin-like domain of a plant aspartic
protease. J. Biol. Chem., 286, 28265-28275.
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| N. V. Pletneva, V. Z.
Pletnev, I. I. Shemiakina, D. M. Chudakov, I. Artemyev, A. Wlodawer, Z. Dauter
and S. Pletnev. 2011. Crystallographic study of red fluorescent protein eqFP578
and its far-red variant Katushka reveals opposite pH-induced isomerization of
chromophore. Protein Sci. 20, 1265-1274. |
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| P. Bhaumik, Y. Horimoto,
H. Xiao, T. Miura, K. Hidaka, Y. Kiso, A. Wlodawer, R. Y. Yada and A.
Gustchina. 1011. Crystal structures of the free and inhibited forms of
plasmepsin I (PMI) from Plasmodium falciparum. J. Struct. Biol., 175,
73-84. |
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| A. Lyskowski, J. S.
Oeemig, A. Jaakkonen, K. Rommi, F. DiMaio, D. Zhou, T. Kajander,
D. Baker, A. Wlodawer, A. Goldman and H. Iwaï.
2011. Cloning, expression, purification, crystallization and preliminary X-ray
diffraction data of Pyrococcus horikoshii RadA intein.
Acta Crystallogr. F67, 623-626. |
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F. DiMaio, T. C.
Terwilliger, R. J. Read, A. Wlodawer, G. Oberdorfer, U. Wagner, E. Valkov, A.
Alon, D. Fass, H. L. Axelrod, D. Das, S. M. Vorobiev, H. Iwaï, P. R.
Pokkuluri and D. Baker. 2011. Improved molecular replacement by density- and
energy-guided protein structure optimization. Nature, 473,
540-543.
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Q. Xu, J. Yao, A.
Wlodawer and H. Guo. 2011. Clarification of the mechanism of acylation reaction
and origin of substrate specificity of the serine-carboxyl peptidase sedolisin
through QM/MM free energy simulations. J. Phys. Chem. B,
115, 2470-2476.
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| M. Li, A. Gustchina, J.
Glesner, S. Wünschmann, L. D. Vailes, M. D. Chapman, A. Pomés
and A. Wlodawer. 2011. Carbohydrates contribute to the interactions between
cockroach allergen Bla g 2 and a monoclonal antibody. J. Immunol.,
186, 333-340. |
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| M. Li, F. DiMaio, D. Zhou,
A. Gustchina, J. Lubkowski, Z. Dauter, D. Baker and A. Wlodawer. 2011. Crystal
structure of XMRV protease differs from the structures of other retropepsins.
Nature Struct. Molec. Biol., 18, 227-229.
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| Z. Miknis, E. Magracheva,
W. Li, A. Zdanov, S. V. Kotenko and A. Wlodawer. 2010. Crystal structure of the
complex of human interferon-λ1 with its high affinity receptor
interferon-λR1. J. Mol. Biol., 404,
650-664. |
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| E.
Gustchina, M. Li, J. M. Louis, D. E. Anderson, J. Lloyd, C. Frisch, C. A.
Bewley, A. Gustchina, A. Wlodawer, and G. M. Clore. 2010. Structural basis of
HIV-1 neutralization by affinity matured Fabs directed against the internal
trimeric coiled-coil of gp41. PLoS Pathogens, e1001182. |
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| T. Satoh, M. Li, J.
T. Nguyen, Y. Kiso, A. Gustchina and A. Wlodawer. 2010. Crystal structures of
inhibitor complexes of human T cell leukemia virus (HTLV-1) protease. J.
Mol. Biol., 401, 626-641. |
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| Mi Li, Alla Gustchina,
Fatima S. Rasulova, Edward E. Melnikov, Michael R. Maurizi, Tatyana V.
Rotanova, Zbigniew Dauter and Alexander Wlodawer. 2010. Structure of the
N-terminal fragment of Escherichia coli Lon protease. Acta
Cryst. D66, 865-873. |
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| N. V. Pletneva, V. Z.
Pletnev, K. A. Lukyanov, N. G. Gurskaya, E. A. Goryacheva, V. I. Martynov, A.
Wlodawer, Z. Dauter, and S. Pletnev. 2010. Structural evidence for a dehydrated
intermediate in green fluorescent protein chromophore biosynthesis. J.
Biol. Chem., 285, 15978–15984. |
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| S. Lee, M. Miller, J. D.
Shuman, and P. F. Johnson. 2010. CCAAT/Enhancer-binding protein β DNA
binding ss auto-inhibited by multiple elements that also mediate association
with p300/CREB-binding protein. J. Biol. Chem., 285,
21399-21410. |
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| S. Lee, J. D. Shuman, T.
Guszczynski, K. Sakchaisri, T. Sebastian, T. D. Copeland, M. Miller, M. S.
Cohen, J. Taunton, R. C. Smart, Z. Xiao, L. R. Yu, T. D. Veenstra, and P. F.
Johnson. 2010.RSK-Mediated phosphorylation in the C/EBPβ leucine zipper
regulates DNA binding, dimerization, and growth arrest activity. Molec and
Cell Bio, 30, 2621–2635. |
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| S. Pletnev, F.
V. Subach, Z. Dauter, A. Wlodawer, and V. V. Verkhusha. 2010. Understanding
blue-to-red conversion in monomeric fluorescent timers and hydrolytic
degradation of their chromophores. J. Am. Chem. Soc., 132, 2243-2253.
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| A. H. Robbins,
R. M. Coman, E. Bracho-Sanchez, M. A. Fernandez, C. T. Gilliland, M. Li, M.
Agbandje-McKenna, A. Wlodawer, B. M. Dunn and R. McKenna. 2010. Crystal
structure of the unbound form of HIV-1 subtype A protease: Comparison with
unbound forms of proteases from other HIV subtypes. Acta Crystallogr.
D66, 233-242. |
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| E. Magracheva,
S. Pletnev, S. Kotenko, W. Li, A. Wlodawer and A. Zdanov. 2010. Purification,
crystallization and preliminary crystallographic studies of the complex of
interferon-λ1 with its receptor. Acta Crystallogr. F66,
61-63. |
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| M. Miller, Z.
Dauter, S. Cherry, J. E. Tropea and A. Wlodawer. 2009. Crystal structure of the
Taz2 domain of p300: Insights into ligand binding. Acta Crystallogr.
D65, 1301-1308. |
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| M. Acchione, C.
A. Lipschultz, M. DeSantis, A. Shanmuganathana, Mi Li, A. Wlodawer, S. Tarasov
and S. J. Smith-Gill. 2009. Light chain somatic mutations change thermodynamics
of binding and water coordination in the HyHel-10 family of antibodies.
Molecular Immunology, 47, 457-464. |
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| S. Pletnev, N.
G. Gurskaya, N. V. Pletneva, K. A. Lukyanov, D. M. Chudakov, V. I. Martynov, V.
O. Popov, M. V. Kovalchuk, A. Wlodawer, Z. Dauter and V. Pletnev. 2009.
Structural basis for phototoxicity of the genetically encoded photosensitizer
KillerRed. J. Biol. Chem., 284, 32028–32039. |
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| S.-M. Yun, T.
Moulaei, D. Lim, J. K. Bang, J.-E. Park, S. R. Shenoy, F. Liu, Y. H. Kang, C.
Liao, N.-K.Soung, S. Lee, D.-Y. Yoon, Y. Lim, D.-H. Lee, A. Otaka, E. Appella,
J. B. McMahon, M. C. Nicklaus, T. R. Burke Jr., M. B. Yaffe, A. Wlodawer, and
K. S. Lee. 2009. Structural and functional analyses of minimal phosphopeptides
targeting the polo-box domain of polo-like kinase 1. Nature Struct. Molec.
Biol., 16, 876-882 . |
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| E. Magracheva,
S. Kozlov, C. L. Stewart, A. Wlodawer and A. Zdanov. 2009. Crystal structure of
the lamin A/C R482W mutant, responsible for the dominant familial partial
lipodystrophy (FPLD). Acta Crystallogr. F65, 665-670. |
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| M. Miller. 2009.
The importance of being flexible: The case of basic region leucine zipper
transcriptional regulators. Current Protein and Peptide Science, 10,
244-269. |
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| P. Bhaumik, H.
Xiao, C. L. Parr, Y. Kiso, A. Gustchina, R. Y. Yada and A. Wlodawer. 2009.
Crystal structure of the histo-aspartic protease (HAP) from Plasmodium
falciparum. J. Mol. Biol., 388, 520-540. |
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| H. Feng, L. M.
Miller Jenkins, S. R. Durell, R. Hayashi, S. J. Mazur, S. Cherry, J. E. Tropea,
M. Miller, A. Wlodawer, E. Appella, Yawen Bai. 2009. Structural basis for p300
Taz2/p53 TAD1 binding and modulation by phosphorylation. Structure, 17,
202-210. |
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| L. M. Miller
Jenkins, H. Yamaguchi, R. Hayashi, S. Cherry, J. E. Tropea, M. Miller, A.
Wlodawer, E. Appella, and S. J. Mazur. 2009. Two distinct motifs within the p53
transactivation domain bind to the Taz2 domain of p300 and are differentially
affected by phosphorylation. Biochemistry, 48,
1244-1255. |
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| J. Davis, J.
Wang, J. E. Tropea, D. Zhang, Z. Dauter, D. S. Waugh and A. Wlodawer. 2008.
Novel fold of VirA, a type III secretion system effector protein from Shigella
flexneri. Protein Sci. 17, 2167-2173. |
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| E. E. Melnikov,
A. G. Andrianova, A. D. Morozkin, A. A. Stepnov, O. V. Makhovskaya, I. Botos,
A. Gustchina, A. Wlodawer, and T. V. Rotanova. 2008. Limited proteolysis of the
E. coli ATP-dependent protease Lon - a unified view of the subunit architecture
and characterization of isolated enzyme fragments. Acta Biochim.
Polon.55, 281-296. |
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| A. S.
Nascimento, S. Krauchenco, A. M. Golubev, A. Gustchina, A. Wlodawer, and I.
Polikarpov. 2008. Statistical coupling analysis of aspartic proteinases based
on crystal structures of the Trichoderma reesei enzyme and its complex with
pepstatin A. J. Mol. Biol., 382, 763-778. |
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| S. Pletnev, D.
Shcherbo, D. Chudakov, N. Pletneva, E. Merzlyak, A. Wlodawer, Z. Dauter, and
Vladimir Pletnev. 2008. A crystallographic study of bright far-red fluorescent
protein mKate reveals pH-induced cis-trans isomerization of the chromophore.
J. Biol. Chem., 283, 2890-2897. |
|
| M. Li, A.
Gustchina, J. Alexandratos, A. Wlodawer, S. Wünschmann, C. L. Kepley, M.
D. Chapman, and A. Pomés. 2008. Crystal structure of a dimerized
cockroach allergen Bla g 2 complexed with a monoclonal antibody. J. Biol.
Chem., 283, 22806-22814. |
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| O. V.
Makhovskaya, S. Kozlov, I. Botos, A. A. Stepnova, A. G. Andrianova, A. E.
Gustchina, A. Wlodawer, E. E. Melnikov, and T. V. Rotanova. 2007. Forms of LonB
protease from Archaeoglobus fulgidus devoid of the transmembrane domain: the
contribution of the quaternary structure to the regulation of enzyme
proteolytic activity. Russ. J. Bioorg. Chem. 33,
610-613. |
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| M. Jaskolski, M.
Gilski, Z. Dauter, and A. Wlodawer. 2007. Numerology versus reality: a voice in
a recent dispute. Acta Crystallogr. D63, 1282-1283. |
|
| T. Moulaei, I.
Botos, N. E. Ziólkowska, H. R. Bokesch, L. R. Krumpe, T. C. McKee, B. R.
O'Keefe, Z. Dauter and A. Wlodawer. 2007. Atomic-resolution crystal structure
of the antiviral lectin scytovirin. Protein Sci. 16,
2756-2760. |
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| N. Pletneva, V.
Pletnev, T. Tikhonova, A. A. Pakhomov, V. Popov, V. I. Martynov, A. Wlodawer,
Z. Dauter and S. Pletnev. 2007. Refined crystal structures of red and green
fluorescent proteins from the button polyp Zoanthus. Acta Crystallogr.
D63, 1082-1093. |
|
| N. V. Pletneva,
S. V. Pletnev, D. M. Chudakov, T. V. Tikhonova, V. O. Popov, V. I. Martynov, A.
Wlodawer, Z. Dauter and V. Z. Pletnev. 2007. Three-dimensional structure of
yellow fluorescent protein zYFP538 from Zoanthus sp. at the resolution of 1.8
Å. Russ. J. Bioorg. Chem. 33, 390-398. |
|
| J. Wang, A.
Wlodawer and Z. Dauter. 2007. What happens when the signs of anomalous
differences or the handedness of substructure are inverted? Acta
Crystallogr. D63, 751-758. |
|
| N. E.
Ziólkowska, S. R. Shenoy, B. R. O'Keefe and A. Wlodawer. 2007.
Crystallographic studies of the complexes of antiviral protein griffithsin with
glucose and N-acetylglucosamine. Protein Sci. 16, 1485-1489
(2007). |
|
| M. Sanches, S.
Krauchenco, N. H. Martins, A. Gustchina, A. Wlodawer and I. Polikarpov. 2007.
Structural characterization of B and non-B subtypes of HIV-protease: insights
into the natural susceptibility to drug resistance development. J. Mol.
Biol., 369, 1029-1040. |
|
| M. Jaskolski, M.
Gilski, Z. Dauter and A. Wlodawer. 2007. Stereochemical restraints revisited:
how accurate are refinement targets and how much should protein structures be
allowed to deviate from them? Acta Crystallogr. D63,
611-620. |
|
| Q. Xu, H. Guo,
A. Wlodawer, T. Nakayama and H. Guo. 2007. The QM/MM molecular dynamics and
free energy simulations of the acylation reaction catalyzed by the serine
carboxyl peptidase kumamolisin-As. Biochemistry, 46,
3784-3792. |
|
| N. E.
Ziólkowska, S. R. Shenoy, B. R. O'Keefe, J. B. McMahon, K. E. Palmer, R.
A. Dwek, M. R. Wormald and A. Wlodawer. 2007. Crystallographic, thermodynamic,
and molecular modeling studies of the mode of binding of oligosaccharides to
the potent antiviral protein griffithsin. Proteins: Struct. Funct.
Bioinform., 67, 661-670. |
|
| N.
LaRonde-LeBlanc, A. N. Santhanam, A. R. Baker, A. Wlodawer, and N. H. Colburn.
2007. Structural basis for inhibition of translation by the tumor suppressor
Pdcd4. Mol. Cell. Biol., 27, 147-156. |
|
| D. R. Demartini,
A. Wlodawer, and C. R. Carlini. 2007. A comparative study of the expression of
serine proteinases in quiescent seeds and in developing Canavalia ensiformis
plants. J. Exper. Botany, 58, 521-532. |
|
| H. Guo, A.
Wlodawer, T. Nakayama, Q. Xu, and H. Guo. 2006. Catalytic role of proton
transfers in the formation of a tetrahedral adduct in a serine carboxyl
peptidase. Biochemistry, 45, 9129-9137. |
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| N. E.
Ziólkowska, B. R. O'Keefe, T. Mori, C. Zhu, B. Giomarelli, F. Vojdani,
K. E. Palmer, J. B. McMahon, and A. Wlodawer. 2006. Domain-swapped structure of
the potent antiviral protein griffithsin and its mode of carbohydrate binding.
Structure, 14, 1127-1135. |
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| Q. Xu, H. Guo,
A. Wlodawer, and H. Guo. 2006. The Importance of dynamics in substrate-assisted
catalysis and specificity. J. Amer. Chem. Soc., 128,
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| M. D. Prasanna,
J. Vondrasek, A. Wlodawer, H. Rodriguez, and T. N. Bhat. 2006. Chemical
compound navigator: A web-based Chem-BLAST, chemical taxonomy based search
engine for browsing compounds. Proteins: Struct., Funct. Bioinf., 63,
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| A. Gustchina, M. Jaskólski, and A.
Wlodawer. 2006. Lessons learned fighting HIV can be applied to anti-cancer drug
design. Cell Cycle, 5, 463-464. |
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| M. Jaskólski, M. Li, G. Laco, A.
Gustchina, and A. Wlodawer. 2006. Molecular replacement with pseudosymmetry and
model dissimilarity: a case study. Acta Crystallogr. D62,
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| C. Xiong, B.
O'Keefe, I. Botos, A. Wlodawer and J. McMahon. 2006. Overexpression and
purification of scytovirin, a potent novel anti-HIV protein from the cultured
cyanobacterium Scytonema varium. Protein Expr Purif., 46,
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| A. Okubo, M.
Li, M. Ashida, H. Oyama, A. Gustchina, K. Oda, B. M. Dunn, A. Wlodawer, and T.
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| M. Miller.
2006. Phospho-Dependent Protein Recognition Motifs Contained in C/EBP Family of
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| M. Li, G. S.
Laco, M. Jaskólski, J. Rozycki, J. Alexandratos, A. Wlodawer, and A.
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novel target for anti-cancer drug design. Proc. Natl. Acad. Sci. USA,
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| H. Guo, A.
Wlodawer, and H. Guo. 2005. A general acid-base mechanism for the stabilization
of tetrahedral adduct in a serine-carboxyl peptidase: a computational study.
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| M. Li, F.
Rasulova, E. E. Melnikov, T. V. Rotanova, A. Gustchina, M. R. Maurizi and A.
Wlodawer. 2005. Crystal structure of the N-terminal domain of E. coli
Lon protease. Protein Science, 14, 2895-2900. |
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| S. Pletnev , E.
Magracheva , A. Wlodawer and A. Zdanov. 2005. A model of the ternary complex of
interleukin-10 with its soluble receptors. BMC Structural Biology 5:10.
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| I. Botos, E. E.
Melnikov, S. Cherry, S. Kozlov, O. V. Makhovskaya, J. E. Tropea, A. Gustchina,
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the proteolytic domain of Archaeoglobus fulgidus Lon reveals the
conformational variability in the active sites of Lon proteases. J. Mol.
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| N.
LaRonde-LeBlanc, T. Guszczynski, T. Copeland and A. Wlodawer. 2005. Structure
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| A. Brik, J.
Alexandratos, Y.-C. Lin, J. H. Elder, A. J. Olson, A. Wlodawer, D. S. Goodsell
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synthesis of HIV-1 protease inhibitors. ChemBioChem 6, 1167-1169.
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| H. Oyama, T.
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| Z. Dauter, I.
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| N.
LaRonde-LeBlanc, T. Guszczynski, T. Copeland and A. Wlodawer. 2005.
Autophosphorylation of A. fulgidus Rio2 and crystal structures of its
nucleotide-metal ion complexes. FEBS Journal, 272,
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| A. Gustchina, M.
Li, S. Wünschmann, M. D. Chapman, A. Pomés and A. Wlodawer. 2005.
Crystal structure of cockroach allergen Bla g 2, an unusual zinc binding
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| H. Zakowicz,
H.-S. Yang, C. Stark, A. Wlodawer, N. LaRonde-LeBlanc and N. H. Colburn. 2005.
Mutational analysis of the DEAD box RNA helicase eIF4AII characterizes its
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| M. D. Prasanna,
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| J.
Tözsér, J. E. Tropea, S. Cherry, P. Bagossi, T. D. Copeland, A.
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| J. Snasel, Z.
Krejcik, V. Jencova, I. Rosenberg, T. Ruml, J. Alexandratos, A. Gustchina and
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| A. M. Yusof, N.
Hu, A. Nögel, M. Schleicher, A. Wlodawer and A. Hofmann. 2005. Structural
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cyclase-associated protein (CAP). Proteins: Struct. Funct. Bioinf., 58,
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| T. V. Rotanova ,
E. E. Melnikov, A. G. Khalatova, O. V. Makhovskaya, I. Botos, A. Wlodawer and
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| P. Forrer, C.
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| N.
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| F. Sheikh, V. V.
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| C. Chang, A.
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| A. Wlodawer, M.
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| I. Botos, E. E.
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| I. Botos, E. E.
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| A. Wlodawer, M.
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| A.
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the sedolisin family of serine-carboxyl peptidases. BMC Structural
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| S. Pletnev, E.
Magracheva, S. Kozlov, G. Tobin, S. V. Kotenko, A. Wlodawer and A. Zdanov.
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interleukin-20 receptors and their complexes with interleukin-19 and
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| M. Miller, J. D.
Shuman, T. Sebastian, Z. Dauter and P. F. Johnson. 2003. Structural basis for
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| C. Gasche, P.
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| A. Wlodawer, M.
Li, A. Gustchina, H. Oyama, B. M. Dunn and K. Oda. 2003. Structural and
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Acta Biochim. Polon., 50, 81-102. |
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| C. Chang, E.
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| J. Lubkowski, M.
Dauter, K. Aghaiypour, A. Wlodawer and Z. Dauter. 2003. Atomic Resolution
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| A. Maurady, A.
Zdanov, D. de Moissac, D. Beaudry and J. Sygusch. 2002. A conserved glutamate
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| J. Phan, A.
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| J. Vondrasek and
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virus protease. Proteins: Struct. Funct. Genet., 49, 429-431. |
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| I. Botos, B. R.
O'Keefe, S. R. Shenoy, L. K. Cartner, D. M. Ratner, P. H. Seeberger, M. R. Boyd
and A. Wlodawer. 2002. Structures of the complexes of a potent anti-HIV protein
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| A. Gustchina, M.
Li, L. H. Phylip, W. E. Lees, J. Kay and A. Wlodawer. 2002. An unusual
orientation for Tyr75 in the active site of the aspartic proteinase from
Saccharomyces cerevisiae. Biochem. Biophys. Res. Commun., 295,
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| A. Hofmann, S.
Hess, A. A. Noegel, M. Schleicher and A. Wlodawer. 2002. Crystallization of
cyclase associated protein from Dictyostelium discoideum. Acta
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| A. Hofmann, H.
Iwai, S. Hess, A. Plückthun and A. Wlodawer. 2002. Crystal structure of
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| I. Botos, T.
Mori, L. K. Cartner, M. R. Boyd, and A. Wlodawer. 2002. Domain-swapped
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| A. Hofmann, S.
Ruvinov, S. Hess, R. Schantz, D. P. Delmer and A. Wlodawer. 2002. Plant
annexins form calcium-independent oligomers in solution. Protein
Science, 11, 2033-2040. |
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| E. K. Jaffe, J.
Kervinen, J. Martins, F. Stauffer, R. Neier, A. Wlodawer and A. Zdanov. 2002.
Species-specific inhibition of porphobilinogen synthase by 4-oxosebacic acid.
J. Biol. Chem., 277, 19792-19799. |
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| L. G.
Barrientos, J. M. Louis, I. Botos, T. Mori, Z. Han, B. R. O'Keefe, M. R. Boyd,
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cyanovirin-N is a metastable folding intermediate. Reconciliation of X-ray and
NMR structures. Structure, 10, 673-686. |
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| A. Hofmann, S.
Tarasov, M. Grella, S. Ruvinov, F. Nasr, W. Filipowicz and A. Wlodawer. 2002.
Biophysical characterization of cyclic nucleotide phosphodiesterases.
Biochem. Biophys. Res. Commun., 291, 875-883. |
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| C. Chang, D. L.
Newton, S. M. Rybak, and A. Wlodawer. 2002. Crystallographic and functional
studies of a modified form of eosinophil-derived neurotoxin (EDN) with novel
biological activities. J. Mol. Biol., 317, 119-130. |
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| A. Hofmann, M.
Grella, I. Botos, W. Filipowicz and A. Wlodawer. 2002. Crystal structures of
the semireduced and inhibitor-bound forms of cyclic nucleotide
phosphodiesterase from Arabidopsis thaliana. J. Biol. Chem., 277,
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| A. Hofmann and
A. Wlodawer. 2002. PCSB - a program collection for structural biology and
biophysical chemistry. Bioinformatics, 18, 209-210. |
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| M. Miller, K.
Ginalski, B. Lesyng, N. Nakaigawa, L. Schmidt and B. Zbar. 2001. Structural
basis of oncogenic activation caused by point mutations in the kinase domain of
the MET proto-oncogene: modeling studies. Proteins, 44, 32-43.
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| A. Wlodawer, M.
Li, A. Gustchina, Z. Dauter, K. Uchida, H. Oyama, N. E. Goldfarb, B. M. Dunn
and K. Oda. 2001. Inhibitor complexes of the Pseudomonas serine-carboxyl
proteinase. Biochemistry, 40, 15602-15611. |
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| I. Botos, Z. Wu,
W. Lu and A. Wlodawer. 2001. Crystal structure of a cyclic form of bovine
pancreatic trypsin inhibitor. FEBS Lett., 509, 90-94. |
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| K. Aghaiypour,
A. Wlodawer and J. Lubkowski. 2001. Do bacterial L-asparaginases utilize a
catalytic triad Glu-Tyr-Thr? Biochim. Biophys. Acta, 1550,
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| J. Kervinen, E.
K. Jaffe, F. Stauffer, R. Neier, A. Wlodawer and A. Zdanov. 2001. Suicide
inactivation of porphobilinogen synthase by 4,7-dioxosebacic acid shows
dramatic species-selectivity. Biochemistry,
40:8227-8236. |
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| C. Chang, A.
Mooser, A. Plückthun and A. Wlodawer. 2001. Crystal structure of the
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| K. Aghaiypour,
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substrate specificity of Erwinia chrysanthemi L-asparaginase.
Biochemistry, 40:5655-5664 |
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| A. Wlodawer, M.
Li, Z. Dauter, A. Gustchina, K. Uchida, H. Oyama, B. M. Dunn, and K. Oda. 2001.
Carboxyl proteinase from Pseudomonas defines a novel family of subtilisin-like
enzymes. Nature Struct. Biol. 8:442-446. |
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| M.
Jaskólski, M. Kozak, J. Lubkowski, G. Palm and A. Wlodawer. 2001.
Crystal structures of two highly homologous bacterial L-asparaginases: a case
of enantiomorphic space groups. Acta Crystallogr.,
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| A. Hofmann, A.
Zdanov, P. Genschik, S. Ruvinov, W. Filipowicz and A. Wlodawer. 2000. Structure
and mechanism of activity of the cyclic phosphodiesterase of Appr>p, a
product of tRNA splicing reaction. EMBO J., 19:6207-6217.
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| F. Yang, P.
Forrer, Z. Dauter, J.F. Conway, N. Cheng, M.E. Cerritelli, A.C. Steven, A.
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of the lambda-phage display platform protein gpD. Nature Struct., Biol.
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| M. Li, L.H.
Phylip, W.E. Lees, J.R. Winther, B.M. Dunn, A. Wlodawer, J. Kay and A.
Gustchina. 2000. The aspartic proteinase from S. cerevisiae folds its own
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| G.J. Palm, E.
Billy, W. Filipowicz and A. Wlodawer. 2000. Crystal structure of RNA
3'-terminal phosphate cyclase, an ubiquitous enzyme with unusual topology.
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| J. Wilken, D.
Hoover, D.A. Thompson, P.N. Barlow, H. McSparron, L. Picard, A. Wlodawer, J.
Lubkowski and S.B.H. Kent. 1999. Total chemical synthesis and high-resolution
crystal structure of the potent anti-HIV protein AOP-RANTES. Chemistry and
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| J. Lubkowski, Z.
Dauter, F. Yang, J. Alexandratos, G. Merkel, A.M. Skalka and A. Wlodawer. 1999.
Atomic resolution structures of the core domain of avian sarcoma virus
integrase and its D64N mutant. Biochemistry, 38:13512-13522
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| J. Kervinen,
G.J. Tobin, J. Costa, D.S. Waugh, A. Wlodawer, and A. Zdanov. 1999. Crystal
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| J. Lubkowski, F.
Hennecke, A. Plückthun, and A. Wlodawer. 1999. Filamentous-phage
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| F. Yang, C.A.
Bewley, J.M. Louis, K.R. Gustafson, M.R. Boyd, A.M. Gronenborn, G.M. Clore, and
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| J. Lubkowski and
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| L. Schmidt, K.
Junker, N. Nakaigawa, T. Kinjerski, G. Weirich, M. Miller, I. Lubensky, H. PH
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mutations of the MET proto-oncogene in papillary renal carcinomas.
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| A. Danilkovitch,
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| J.K.M. Rao, G.
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| M. Miller, M.
Baca, J.K.M. Rao, and S.B.H. Kent. 1998. Probing the structural basis of the
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| M. Miller and
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| |
|
| REVIEWS AND
MONOGRAPHS: |
|
| |
|
| A. Wlodawer
and M. Jaskolsk. 2016. Inhibitors of HIV protease. Encyclopedia of Cell
Biology, Ralph A. Bradshaw and Philip D. Stahl (Editors-in-Chief), Vol 1,
Waltham, MA: Academic Press, pp. 738-745. |
|
| M.
Jaskolski, M. Miller, J.K.M. Rao, A. Gustchina and A. Wlodawer. 2015.
Elucidation of the structure of retroviral proteases: a reminiscence. FEBS
J., 282, 4059-4066. |
|
| A. Wlodawer.
2015. First protein crystallography experiments on a synchrotron.
Synchrotron Radiation News, 28:4, 28-29. |
|
| A.
Pomés, M. Chruszcz, A. Gustchina, W. Minor, G. A. Mueller, L. C.
Pedersen, A. Wlodawer and M. D. Chapman. 2015. 100 years later: Celebrating the
contributions of X-ray crystallography to allergy and clinical immunology.
J. Allergy Clin. Immunol., 136, 29-37. |
|
| M. Jaskolski
and A. Wlodawer. 2014 Celebrating the International Year of Crystallography.
FEBS J., 281, 3983-3984. |
|
| M.
Jaskolski, Z. Dauter and A. Wlodawer. 2014. A brief history of macromolecular
crystallography, illustrated by a family tree and its Nobel fruits. FEBS
J., 281, 3985-4009. |
|
| H. Zheng, J.
Hou, M. D. Zimmerman, A. Wlodawer and W. Minor. 2014. The future of
crystallography in drug discovery. Expert Opin. Drug Discov., 9,
125-137. |
|
| B. M. Dunn and A.
Wlodawer. 2013. The regulation of proteolysis around the World, Current
Opin. Struct. Biol., 23, 1-2. |
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| A. Wlodawer, W. Minor, Z.
Dauter and M. Jaskolski. 2013. Protein crystallography for aspiring
crystallographers, or how to avoid pitfalls and traps in macromolecular
structure determination. FEBS J., 280, 5705-5736. |
|
J. Kervinen and A.
Wlodawer. 2013. Chapter 23 – Phytepsin, in Handbook of
Proteolytic Enzymes (Third Edition), N. D. Rawlings and G. Salvesen
(Eds.), vol. 1, Elsevier Ltd., London, England, pp.
118-124.
|
|
| A. Wlodawer, A. Gustchina
and M. N. G. James. 2013. Chapter 2 – Catalytic Pathways of Aspartic
Peptidases, in Handbook of Proteolytic Enzymes (Third Edition), N. D.
Rawlings and G. Salvesen (Eds.), vol. 1, Elsevier Ltd., London, England, pp.
19-26. |
|
| P. Bhaumik, A. Gustchina
and A. Wlodawer. 2012. Structural studies of vacuolar plasmepsins. BBA -
Proteins and Proteomics, 1824, 207-223. |
|
| M. Jaskolski, J. N.
Alexandratos, G. Bujacz and A. Wlodawer. 2011. Structural studies of retroviral
integrases. in “HIV-1 Integrase: Mechanism and Inhibitor Design,” N.
Neamati ed., pp. 35-49, Wiley, NY. |
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| A. Zdanov. 2010.
Structural analysis of cytokines comprising the IL-10 family. Cytokine
& Growth Factor Reviews, 21, 325–330. |
|
M. Chruszcz, M.
Domagalski, T. Osinski, A. Wlodawer and W. Minor. 2010. Unmet challenges of
structural genomics. Curr. Opin. Struct. Biol., 20,
587-597.
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|
A. Wlodawer, J.
Lubkowski, M. Minor and M. Jaskolski. 2010. Is too "creative" language
acceptable in crystallography? Acta Crystallogr. D66,
1041-1042.
|
|
| Z. Dauter, M.
Jaskolski, and A. Wlodawer. 2010. Impact of synchrotron radiation on
macromolecular crystallography: A personal view. J. Synchr. Rad., 17,
433-444. |
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| M. Miller. 2009. Invited
review: The early years of retroviral rrotease crystal structures. Peptide
Science, 94, 521-529. |
|
| Z. Dauter and A.
Wlodawer. 2009. Proteins do not have strong spines after all. Structure
17, 1278-1279 (2009). |
|
| M. Jaskolski, J.
N. Alexandratos, G. Bujacz and A. Wlodawer. 2009. Piecing together the
structure of retroviral integrase, an important target in AIDS therapy. FEBS
J., 276, 2926-2946. |
|
| M. Chruszcz, A.
Wlodawer and W. Minor. 2008. Determination of protein structures - a series of
fortunate events. Biophys. J., 95, 1-9. |
|
| A. Zdanov and A.
Wlodawer. 2008. A new look at cytokine signaling. Cell 132,
179-181. |
|
| A. Wlodawer, W.
Minor, Z. Dauter, and M. Jaskolski. 2008. Protein crystallography for
non-crystallographers or how to get the best (but not more) from the published
macromolecular structures. FEBS J., 275, 1-21. |
|
| I. Botos and A.
Wlodawer. 2007. The expanding diversity of serine hydrolases. Curr. Opin.
Struct. Biol., 17, 683-690. |
|
| A. Wlodawer.
2007. Deposition of structural data redux. Acta Crystallogr. D63,
421-423. |
|
| N. E.
Ziólkowska and A. Wlodawer. 2006. Structural studies of algal lectins
with anti-HIV activity. Acta Biochim. Polon., 53,
617-626. |
|
| T. V. Rotanova,
I. Botos, E.E. Melnikov, F. Rasulova, A. Gustchina, M. R. Maurizi, and A.
Wlodawer. 2006. Slicing a protease: structural features of the ATP-dependent
Lon proteases gleaned from investigations of isolated domains. Protein
Sci. 15, 1815-1828 (2006). |
|
| N.
LaRonde-LeBlanc and A. Wlodawer. 2005. A family portrait of the RIO kinases.
J. Biol. Chem., 280, 37297-37300. |
|
| N.
LaRonde-LeBlanc and A. Wlodawer. 2005. The RIO kinases: An atypical protein
kinase family required for ribosome biogenesis and cell cycle progression.
Biochim. Biophys. Acta, 1754, 14-24. |
|
| A. Wlodawer.
2004. How to kill an enzyme (in more ways than one). Structure, 12,
1117-1119. |
|
| A. Zdanov. 2004.
Structural features of the Interleukin-10 family of cytokines. Current
Pharmaceutical Design, 10, 3873-3874. |
|
| J. Kervinen, A.
Wlodawer and A. Zdanov. 2004. Phytepsin. In Handbook of proteolytic
enzymes, 2nd Edition, A. J. Barrett, N. D. Rawlings and J. F.
Woessner, eds., Elsevier Ltd., London, England, pp. 77-84. |
|
| I. Botos and A.
Wlodawer. 2005. Proteins that bind high-mannose sugars of the HIV envelope.
Prog. Biophys. Molec. Biol., 88, 233-282. |
|
| I. Botos and A.
Wlodawer. 2003. Cyanovirin-N - a sugar-binding antiviral protein with a new
twist. Cell Mol Life Sci., 60, 277-87. |
|
| A. Wlodawer.
2002. Structure-based design of AIDS drugs and the development of resistance.
Vox Sang. 83 (Suppl. 1), 23-26. |
|
| B. M. Dunn, M.
M. Goodenow, A. Gustchina and A. Wlodawer. 2002. Retroviral proteases.
Genome Biology, 3, 3006.1-3006.7. |
|
| A. Wlodawer.
2002. Rational approach to AIDS drug design through structural biology. Ann.
Rev. Med., 53, 595-614. |
|
| Wlodawer, A.,
and A. Gustchina. 2000. Structural and biochemical studies of retroviral
proteases. Biochim. Biophys. Acta, 1477:16-34. |
|
| Wlodawer, A.,
and J. Vondrasek. 1998. Inhibitors of HIV-1 protease: A major success of
structure-assisted drug design. Annu. Rev. Biophys. Biomol. Struct.,
27:249-284. |
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| OLDER
PUBLICATIONS: |
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| Powell, D.J., D.
Bur, A. Wlodawer, A. Gustchina, B.M. Dunn, and J. Kay. 1998. The aspartic
proteinase from equine infectious anaemia virus. Adv. Exp. Med. Biol.,
436:41-45. |
|
| Dodson, G., and
A. Wlodawer. 1998. Catalytic triads and their relatives. Trends Biochem.
Sci., 23:347-352. |
|
| Alexandratos,
J., G. Bujacz, M. Jaskólski, A. Wlodawer, G. Merkel, R.A. Katz, and A.M.
Skalka. 1997. Crystal structure of avian sarcoma virus integrase with bound
essential cations. In Techniques in Protein Chemistry VIII (D.R.
Marshak, ed.), Academic Press, pp. 417-425. |
|
| Schalk-Hihi, C.,
J. Lubkowski, A. Zdanov, A. Wlodawer, A. Gustchina, G.S. Laco, and J.H. Elder.
1997. Structure of the D30N active site mutant of FIV proteinase complexed with
a statine-based inhibitor. In Techniques in Protein Chemistry VIII (D.R.
Marshak, ed.), Academic Press, pp. 643-654. |
|
| Vondrasek, J.,
and A. Wlodawer. 1997. Database of HIV proteinase structures. Trends
Biochem. Sci., 22:183. |
|
|
Hodge, C.N., T.P. Straatsma, J.A.
McCommon, and A. Wlodawer. 1997. Rational design of HIV protease inhibitors. In
Structural Biology of Viruses (W. Chiu, ed.), Oxford University Press.
|
|
| Vondrasek, J.,
and A. Wlodawer. 1997. Database of three-dimensional structures of HIV
proteinases. Nat. Struct. Biol., 4:8. |
|
| Bujacz, G., M.
Jaskólski, J. Alexandratos, A. Wlodawer, G. Merkel, R.A. Katz, and A.M.
Skalka. 1996. Crystal structure of the catalytic domain of avian sarcoma virus
integrase. In Techniques in Protein Chemistry VII (D.R. Marshak, ed.),
Academic Press, pp. 383-390. |
|
| Rao, J.K.M., M.
Gribskov, J. Lubkowski, M. Miller, A.L. Swain, and A. Wlodawer. 1996. A
comparison of the crystal structures of bacterial L-asparaginases. In
Techniques in Protein Chemistry VII (D.R. Marshak, ed.), Academic Press,
pp. 373-381. |
|
| Vondrasek, J.,
and A. Wlodawer. 1996. New database. Science, 272:337-338.
|
|
| Wlodawer, A.
1995. Inhibitor complexes of HIV-1 protease in AIDS. In Molecular Biology
and Biotechnology (R.A. Myers, ed.), VCH Publishers Inc., New York, NY, pp.
6-10. |
|
| Cameron, C.E.,
H. Burstein, D. Bizub-Bender, T. Ridky, I.T. Weber, A. Wlodawer, A.M. Skalka,
and J. Leis. 1995. Identification of amino acid residues of the retroviral
aspartic proteinases important for substrate specificity and catalytic
efficiency. Adv. Exp. Med. Biol., 362:399-406. |
|
| Wlodawer, A.
1995. Proteasome: A complex protease with a new fold and a distinct mechanism.
Structure, 3:417-420. |
|
|
Davies, D.R., and A. Wlodawer. 1995.
Cytokines and their receptor complexes. FASEB J., 9:50-56.
|
|
| Dunn, B.M., A.
Gustchina, A. Wlodawer, and J. Kay. 1994. Subsite preferences of retroviral
proteinases. Methods Enzymol., 241:254-278. |
|
| Wlodawer, A.,
and J.W. Erickson. 1993. Structure-based inhibitors of HIV-1 protease. Annu.
Rev. Biochem., 62:543-585. |
|
| Wlodawer, A.
1992. Inhibitor complexes of HIV-1 protease: A target for drug design. In
Proceedings of the Robert A. Welch Foundation Conference on Chemical
Research XXXV, Houston, TX, pp. 71-84. |
|
| Wlodawer, A.,
A.L. Swain, and A. Gustchina. 1992. Comparison of crystal structures of
inhibitor complexes of the human immunodeficiency virus protease. In
Molecular Aspects of Chemotherapy (D. Shugar, W. Rode, and E. Borowski,
eds.), Polish Scientific Publishers, pp. 173-186. |
|
| Sjölin, L.,
A. Wlodawer, G. Bergqvist, P. Holm, K. Loth, H. Malmstrom, J. Zaar, L.A.
Svensson, J. Dill, and G.L. Gilliland. 1992. Protein crystals grown on board
MASER-3 extend the ribonuclease-A structure to 1.06 Å resolution. In
SP-1132, Vol. 2, European Space Agency, pp. 92-103. |
|
| Swain, A., A.
Gustchina, and A. Wlodawer. 1992. Comparison of three inhibitor complexes of
human immunodeficiency virus protease. In Structure and Function of the
Aspartic Proteinase: Genetics, Structure, and Mechanisms (B. Dunn, ed.),
Plenum Press, New York, NY, pp. 433-441. |
|
| Wlodawer, A., M.
Miller, A. Swain, and M. Jaskólski. 1991. Structures of three inhibitor
complexes of HIV-1 proteases. In Methods in Protein Sequence Analysis
(H. Jornvall, J.-O. Hoog, and A.-M. Gustavsson, eds.), Birkhauser Verlag,
Basel, Switzerland, pp. 215-221. |
|
| Baldwin, E., J.
Sussman, R. St. Charles, and A. Wlodawer. 1991. Molecular replacement structure
solution of interleukin-8 using the NMR model. In Techniques in Protein
Chemistry II (J.J. Villafranca, ed.), Academic Press, San Diego, CA, pp.
347-356. |
|
| Sjölin, L.,
A. Wlodawer, G. Bergqvist, P. Holm, K. Loth, H. Malmstrom, J. Zaar, L.A.
Svensson, J. Dill, and G.L. Gilliland. 1991. Protein crystals grown aboard
MASER-3 extend the ribonuclease-A structure to 1.06 Å resolution. In
Structure, Mechanism, and Function of Ribonucleases (C.M. Cuchillo, R.
de Llorens, M.V. Nogues, and X. Pares, eds.), IBF Publications, Barcelona,
Spain, pp. 39-50. |
|
| Gustchina, A.,
I.T. Weber, and A. Wlodawer. 1991. Molecular modeling of HIV-2 protease. In
Structure and Function of the Aspartic Proteinases (B.M. Dunn, ed.),
Plenum Press, New York, NY, pp. 549-553. |
|
| Miller, M., A.L.
Swain, M. Jaskólski, B.K. Sathyanarayana, G.R. Marshall, D.H. Rich,
S.B.H. Kent, and A. Wlodawer. 1990. X-ray analysis of HIV-1 protease and its
complexes with inhibitors. In Retroviral Proteases: Control of Maturation
and Morphogenesis (L. Pearl, ed.), MacMillan Press, pp. 93-106.
|
|
| Erickson, J.,
J.K.M. Rao, C. Abad-Zapatero, and A. Wlodawer. 1989. Structural comparisons of
retroviral and eukaryotic aspartic proteinases. In Viral Proteinases as
Targets for Chemotherapy (H.-G. Krausslich, S. Oroszlan, and E. Wimmer,
eds.), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp.
191-210. |
|
| Miller, M., M.
Jaskólski, J.K.M. Rao, A. Wlodawer, and J. Leis. 1989. Preliminary
crystallographic investigation of a protease from Rous sarcoma virus. In
Proteases of Retroviruses (V. Kostka, ed.), Walter de Gruyter, West
Berlin, Germany, pp. 165-174. |
|
| Jaskólski, M., M. Miller, J.K.M. Rao, J. Leis, and A.
Wlodawer. 1989. Structure of the aspartic proteinase from Rous sarcoma
retrovirus at 2 Å resolution. In Viral Proteinases as Targets for
Chemotherapy (H.-G. Krausslich, S. Oroszlan, and E. Wimmer, eds.), Cold
Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 175-180.
|
|
| Foundling, S.I.,
F.R. Salemme, B. Korant, J.J. Wendoloski, P.C. Weber, A.C. Treharne, M.C.
Schadt, M. Jaskólski, M. Miller, A. Wlodawer, P. Strop, V. Kostka, J.
Sedlacek, and D.H. Ohlendorf. 1989. Crystal structure of a retroviral protease
from avian myeloblastosis associated virus. In Viral Proteinases as Targets
for Chemotherapy (H.-G. Krausslich, S. Oroszlan, and E. Wimmer, eds.), Cold
Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 181-190.
|
|
| Leis, J., D.
Bizub, I.T. Weber, C. Cameron, R. Katz, A. Wlodawer, and A.M. Skalka. 1989.
Structure-function analysis of retroviral aspartic protease. In Viral
Proteinases as Targets for Chemotherapy (H.-G. Krausslich, S. Oroszlan, and
E. Wimmer, eds.), Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY,
pp. 235-243. |
|
| Nachman, J., M.
Miller, G.L. Gilliland, R. Carty, M. Pincus, and A. Wlodawer. 1989. Crystal
structure of two covalent nucleoside derivatives of ribonuclease A. In
Structure and Chemistry of Ribonucleases (A. Pavlovsky and K. Polyakov,
eds.), IUCR, Moscow, USSR, pp. 22-30. |
|
| Wlodawer, A.,
G.L. Gilliland, L. Sjölin, and L.A. Svensson. 1987. Crystal structure of
phosphate-free ribonuclease. In Protein Structure and Design, UCLA Symposia
on Molecular and Cellular Biology, New Series, Vol. 69, pp. 109-118.
|
|
| Harrison, R.W.,
I.T. Weber, H.L. Ammon, K.C. Murphy, A. Wlodawer, G.L. Gilliland, and J.
Roberts. 1987. Crystal structures of bacterial glutaminase–asparaginases.
In Protein Structure and Design, UCLA Symposia on Molecular and Cellular
Biology, New Series, Vol. 69, pp. 83-92. |
|
| Raghavan, N.V.,
and A. Wlodawer. 1987. Neutron crystallography of proteins. In Methods in
Experimental Physics: Neutron Scattering, Vol. 23 (K. Sköld and D.L.
Price, eds.), Academic Press, Orlando, FL, pp. 335-365. |
|
| Savage, H., and
A. Wlodawer. 1986. Determination of water structure around biomolecules using
X-ray and neutron diffraction methods. Methods Enzymol., 127:162-183.
|
|
| Wlodawer, A.
1985. Neutron diffraction: A facility for data collection and processing at the
National Bureau of Standards reactor. Methods Enzymol., 114:551-564.
|
|
| Wlodawer, A.
1984. Structure of bovine pancreatic ribonuclease. In Biological
Macromolecules and Assemblies, Vol. II: Nucleic Acids and Interactive
Proteins (A. McPherson and F. Jurnak, eds.), John Wiley, New York, NY, pp.
393-439. |
|
| Gunning, J., S.
Bedarkar, G.L. Taylor, J.M. Goodfellow, T.L. Blundell, A. Wlodawer, K.O.
Hodgson, E.M. Shooter, R. Fourme, B. Gaber, and R. Williams. 1982.
Conformational studies of polypeptide growth factors: IGF and NGF. Prog.
Clin. Biol. Res. 102A:221-230. |
|
| Wlodawer, A.
1982. Neutron diffraction of crystalline proteins. Prog. Biophys. Mol.
Biol., 40:115-159. |
|
| Phillips, J.C.,
A. Wlodawer, and K.O. Hodgson. 1976. On the application of synchrotron
radiation to X-ray diffraction: Polarization and anomalous scattering.
Stanford Synchrotron Radiation Project, SSRP-76/01, Stanford University,
Stanford, CA. |
|
| Lubas, B., A.
Blum, and A. Wlodawer. 1975. Fourier transform NMR spectroscopy and its
application in the studies of conformational changes of proteins with low
molecular weight. In Proceedings of the 8th Symposium on NMR
Applications, Cracow, Poland, pp. 185-198. |
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