Catalytic RNAs

Gene regulatory RNAs

RNA in signal transduction

RNA-protein interactions

RNA analogs of GFP

Small molecule recognition by RNA

RNA folding and dynamics

Molecular evolution

Methods

In addition to serving as a carrier of genetic information, RNA can adopt complex three-dimensional structures that bind other molecules with high specificity, and precisely position functional groups. We study the biophysical underpinnings for this molecular versatility, and how organisms exploit it in the control of cellular physiology.

Catalytic RNAs	Gene regulatory RNAs	RNA in signal transduction
RNA-protein interactions	RNA analogs of GFP	Small molecule recognition by RNA
RNA folding & dynamics	Molecular evolution	Methods